用於治療主體中害病的或受損的組織之方法，包括針對該主體害病的或受損組 織發生處給予健康組織（相對應於該害病的或受損的組織處）中之一般形式細胞， 及／或其適當之前驅細胞（progenitor cell），結合生物可吸收之微珠或顆粒， 並可選擇性混合凝膠及／或凝膠生成物質。其中該細胞及／或適當之前驅細胞為軟 骨細胞、胚胎幹細胞及／或骨髓基質細胞；本發明方法適用於治療，例如，與初級 骨關節炎相關之關節軟骨退化現象。於此亦揭露一具類似組織特性之裝置，用以治 療主體中害病的或受損的組織，其中該裝置包含健康組織（相對應於該害病的或受 損組織處）中之一般形式細胞，及／或其適當之前驅細胞，結合生物可吸收之微珠 或顆粒，並可選擇性混合凝膠及／或凝膠生成物質。 Methods for treating diseased or damaged tissue in a subject are disclosed, involving administering to said subject at a site wherein diseased or damaged tissue occurs, cells of a type(s) normally found in healthy tissue corresponding to the diseased or damaged tissue, and/or suitable progentior cells thereof, in association with bioresorbable beads or particles and optionally a gel and/or gel-forming substance. Where the cells and/or suitable progentior cells thereof are chondrocytes, embryonic stem cells and/or bone marrow stromal cells, the methods of the invention are suitable for treating, for example, articular cartilage degeneration associated with primary osteoarthritis. Also disclosed is a device having tissue-like characteristics for treating diseased or damaged tissue in a subject, wherein the device comprises cells of a type(s) normally found in healthy tissue corresponding to the diseased or damaged tissue, and/or suitable progenitor cells thereof, in association with bioresorbable beads or particles and optionally a gel and/or gel-forming substance.
用於治療主體中害病的或受損的組織之方法，包括針對該主體害病的或受損組 織發生處給予健康組織（相對應於該害病的或受損的組織處）中之一般形式細胞， 及／或其適當之前驅細胞（progenitor cell），結合生物可吸收之微珠或顆粒， 並可選擇性混合凝膠及／或凝膠生成物質。其中該細胞及／或適當之前驅細胞為軟 骨細胞、胚胎幹細胞及／或骨髓基質細胞；本發明方法適用於治療，例如，與初級 骨關節炎相關之關節軟骨退化現象。於此亦揭露一具類似組織特性之裝置，用以治 療主體中害病的或受損的組織，其中該裝置包含健康組織（相對應於該害病的或受 損組織處）中之一般形式細胞，及／或其適當之前驅細胞，結合生物可吸收之微珠 或顆粒，並可選擇性混合凝膠及／或凝膠生成物質。 Methods for treating diseased or damaged tissue in a subject are disclosed, involving administering to said subject at a site wherein diseased or damaged tissue occurs, cells of a type(s) normally found in healthy tissue corresponding to the diseased or damaged tissue, and/or suitable progentior cells thereof, in association with bioresorbable beads or particles and optionally a gel and/or gel-forming substance. Where the cells and/or suitable progentior cells thereof are chondrocytes, embryonic stem cells and/or bone marrow stromal cells, the methods of the invention are suitable for treating, for example, articular cartilage degeneration associated with primary osteoarthritis. Also disclosed is a device having tissue-like characteristics for treating diseased or damaged tissue in a subject, wherein the device comprises cells of a type(s) normally found in healthy tissue corresponding to the diseased or damaged tissue, and/or suitable progenitor cells thereof, in association with bioresorbable beads or particles and optionally a gel and/or gel-forming substance.