NOVEL PYRIDINE ALKALOIDS, PREPARATION PROCESS THEREOF, AND THE USES OF THE PYRIDINE ALKALOIDS - 經濟部產業技術司–專利資料集 @ 經濟部
專利名稱-中文NOVEL PYRIDINE ALKALOIDS, PREPARATION PROCESS THEREOF, AND THE USES OF THE PYRIDINE ALKALOIDS的核准國家是美國, 執行單位是食品所, 產出年度是105, 專利性質是發明, 計畫名稱是生物資源的系統營運與產業應用四年計畫, 專利發明人是吳明德、鄭銘仁、林錫杰、陳紀樺、陳彥霖、陳慧屏、陳凱萍、楊秉勳、陳秀雯、袁國芳, 證書號碼是9474774.
The present invention relates to novel pyridine alkaloid compounds of formula (I): ##STR00001## or a pharmaceutically acceptable derivative thereof as described in the specification, the process for the preparation of the same, and the composition comprising the same. The uses of a pyridine compound for increasing the activity of PPAR.gamma., for the prevention and/or treatment of a disease or disorder related to insulin resistance, and for the prevention and/or treatment of metabolic syndrome or its complication are also provided. The invention also provides extracts of red yeast-fermented products and their uses for prevention and/or treatment of a disease or disorder related to insulin resistance, such as metabolic syndrome.
The present invention relates to novel pyridine alkaloid compounds of formula (I): ##STR00001## or a pharmaceutically acceptable derivative thereof as described in the specification, the process for the preparation of the same, and the composition comprising the same. The uses of a pyridine compound for increasing the activity of PPAR.gamma., for the prevention and/or treatment of a disease or disorder related to insulin resistance, and for the prevention and/or treatment of metabolic syndrome or its complication are also provided. The invention also provides extracts of red yeast-fermented products and their uses for prevention and/or treatment of a disease or disorder related to insulin resistance, such as metabolic syndrome.
To provide novel pyridine alkaloids, the preparation process thereof and the uses of the same. ;SOLUTION: This invention relates to: novel pyridine alkaloid compounds of formula (I), or a pharmaceutically acceptable derivative thereof; the process for preparing the same; and a composition with the same. This invention also relates to the uses of a pyridine compound for increasing the activity of PPAR[gamma], for prevention and/or treatment of a disease or disorder related to insulin resistance, and for prevention and/or treatment of metabolic syndrome or its complication. This invention further relates to extracts of red yeast-fermented products and their uses for prevention and/or treatment of a disease or disorder related to insulin resistance, such as metabolic syndrome.
技術摘要-中文: To provide novel pyridine alkaloids, the preparation process thereof and the uses of the same. ;SOLUTION: This invention relates to: novel pyridine alkaloid compounds of formula (I), or a pharmaceutically acceptable derivative thereof; the process for preparing the same; and a composition with the same. This invention also relates to the uses of a pyridine compound for increasing the activity of PPAR[gamma], for prevention and/or treatment of a disease or disorder related to insulin resistance, and for prevention and/or treatment of metabolic syndrome or its complication. This invention further relates to extracts of red yeast-fermented products and their uses for prevention and/or treatment of a disease or disorder related to insulin resistance, such as metabolic syndrome.